Preface Acknowledgements PartⅠ:Principles of Cell Biology and Molecular Genetics 1.General Organization of the cell Cell concept Structure and function of cellular organelles 2.Proteins and Enzymes Amino acids Proteins Enzymes 3.The Cell Membrane Structure of the cell membrane Transport across the cell membrane Membrane potential Receptors 4.The Working Cell Cytoskeleton and cell motility Lysosomes Cell surface and cell adhesion 5.The Molecular Basis of Genetics Organization of the cell nucleus Cell cycle Mitosis and meiosis Structure and properties of nucleic acids DNA packaging and repair DNA replication Transcription of DNA Genetic code Translation and protein synthesis Post-translational modification of proteins Genetics of bacteria and viruses PartⅡ:Medical Genetics 6.Principles of Medical Genetics Patterns of inheritance Genetics in disease Risk assessment and genetic counselling Population genetics and screening Recombinant DNA technology as applied to medicine 7.The Genetic Consultation Genetic consultation and history taking Common presentations of genetic disease 8.Examples of Genetic Disease Chromosomal disorders Trinucleotide repeat disorders Single gene disorders Genetic cancer syndromes Congenital malformations PartⅣ:Self-assessment Multiple-choice Questions Short-answer Questions Essay Questions MCQ Answers SAQ Answers Index
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